Apigenin

ScientificNameLabel

Apigenin
PHCD compound ID :	1003
Chemical Names :	Apigenin , Apiginen
Molecular Formula :	C15H10O5
Molecular Weight :	270.052823

More Details :

Names & Synonyms:	5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one , 5,7-dihydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one , 2-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one , 5,7-dihydroxy-2-(4-hydroxyphenyl)chromone
Smiles:	Oc1ccc(cc1)c1cc(=O)c2c(o1)cc(cc2O)O
InChi :	InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChi Key :	InChIKey=KZNIFHPLKGYRTM-UHFFFAOYSA-N
PubChem ID :	5280443

Rotatable bond count :	1	Rule of five :	0
Hydrogen bond acceptor count :	5	Ionization potential :	9.411237
Hydrogen bond donor count :	3	Electric dipole moment :	3.492
XLogP :	1.138	VDW volume :	231.986316
Molecular weight :	270.052823	HOMO-LUMO gap :	8.351000

Herb list :

Anis estrellado, Star anise - Illicium verum - انیسون ستاره‌ای، بادیان خَتایی

Artichoke - Cynara scolymus - کنگر فرنگی، آرتیشو

Barley - Hordeum vulgare - جو

Cacao tree - Theobroma cacao - کاکائو

Caper - Capparis spinosa - کبر، لگجی، علف مار، کور

Celandine, Swallowwort - Chelidonium majus L - مامیران

Chamomile - Matricaria chamomilla - بابونه شيرازی، بابونه

Common purslane - Portulaca oleracea - خرفه

Cotton thistle, Scotch thistle - Onopordon acanthium - خار پنبه، خار پیرزن

Cutleaf teasel - Dipsacus laciniatus - خواجه‌ باشی

Egyptian willow - Salix aegyptiaca - بيدمشك

European verbena, Vervain - Verbena officinalis L - شاه پسند

Hawthorn - Crataegus microphylla - سرخه ولیک، سرخ ولیک، زالزالک برگ ریز

Henna - Lawsonia inermis - حنا

High mallow, Marsh mallow, Wild mallow - Malva sylvestris - پنیرک قرمز، پنیرک

Maypop, Purple passionflower, True passionflower - Passiflora incarnata - گل ساعتی، پیچ ساعتی

Mountain tobacco - Arnica montana - تنباکوی کوهی

Parsley - Petroselinum crispum (Miller) A.W.Hill - جعفری

Pistacio - Pistacia vera - پسته

Pomegranate - Punica granatum - گلنار، انار

Real tobacco - Nicotiana rustica - توتون

Sumac - Rhus coriaria - سماق

Watercress - Nasturtium officinale - بولاغ اوتی، آب تره، علف چشمه، ترتیزک آبی

White water lily - Ipomea purpura - نیلوفر آبی سفید، لاله مردابی سید

Will fumitory - Fumaria officinalis - شاه تره

Refrences & Litretures:


99. Journal:'Industrial Crops and Products' Year:'2013' Volume:'44' Page:'437' DOI:'10.1016/j.indcrop.2012.10.012' Title:'Antioxidant and antimicrobial activities of essential oil and extracts of fennel (Foeniculum vulgare L.) and chamomile (Matricaria chamomilla L.)'
175. Journal:'Zeb SpringerPlus' Year:'2015' Volume:'4' Page:'714' DOI:'10.1186/s40064-015-1514-5' Title:'Phenolic profile and antioxidant potential of wild watercress (Nasturtium officinale L.)'
185. Journal:'Nutrition and Cancer' Year:'2013' Volume:'65' Page:'1045' DOI:'10.1080/01635581.2013.850966' Title:'Anticarcinogenic Effects of the Ethanolic Extract of Salix aegyptiaca in Colon Cancer Cells: Involvement of Akt/PKB and MAPK Pathways'
200. Journal:'Biochimie' Year:'2010' Volume:'92' Page:'1115' DOI:'10.1016/j.biochi.2010.03.027' Title:'Antioxidant activity and phenolic pro?le of pistachio (Pistacia vera L., variety Bronte) seeds and skins'
210. Journal:'THE PHARMA INNOVATION' Year:'2014' Volume:'3' Page:'46' DOI:'' Title:'Research phenolic compounds Malva sylvestris by high performance liquid chromatography'
253. Journal:'Chemistry Central Journal' Year:'2012' Volume:'6' Page:'97' DOI:'' Title:'Evaluation of antioxidant and cytoprotective activities of Arnica montana L. and Artemisia absinthium L. ethanolic extracts'
268. Journal:'Allelopathy Journal' Year:'2009' Volume:'24' Page:'225' DOI:'' Title:'Allelopathic Plants. 19. Barley (Hordeum vulgare L)'
289. Journal:'International Journal of Pharmaceutical Sciences and Drug Research' Year:'2010' Volume:'2' Page:'91' DOI:'' Title:'Lawsonia inermis Linnaeus: A Phytopharmacological Review'
309. Journal:'BioMed Research International' Year:'2015' Volume:'' Page:'925631' DOI:'10.1155/2015/925631' Title:'Portulaca oleracea L.: A Review of Phytochemistry and Pharmacological Effects'
313. Journal:'Journal of Pharmaceutical and Biomedical Analysis' Year:'2006' Volume:'41' Page:'493' DOI:'10.1016/j.jpba.2006.01.013' Title:'Determination of ?avonoids in Portulaca oleracea L. by capillary electrophoresis with electrochemical detection'
434. Journal:'Natural Product Research' Year:'2004' Volume:'18' Page:'211' DOI:'10.1080/14786410310001620673' Title:'FLAVONOIDS OF CRATAEGUS MICROPHYLLA'
443. Journal:'Food Chemistry' Year:'2015' Volume:'166' Page:'179' DOI:'10.1016/j.foodchem.2014.06.011' Title:'HPLC–DAD–ESI-MS/MS screening of bioactive components from Rhus coriaria L. (Sumac) fruits'
475. Journal:'Int. J. Curr. Microbiol. App. Sci' Year:'2014' Volume:'3' Page:'296' DOI:'' Title:'Antioxidant activities and phenolic compounds in Bulgarian Fumaria species'
569. Journal:'J. Mass Spectrom' Year:'2003' Volume:'38' Page:'35' DOI:'10.1002/jms.395' Title:'Liquid chromatographic/electrospray ionization tandem mass spectrometric study of the phenolic composition of cocoa (Theobroma cacao)'
579. Journal:'Int J Diabetol Vasc Dis Res' Year:'2015' Volume:'3' Page:'99' DOI:'10.19070/2328-353X-1500020' Title:'Pharmacological Properties of Capparis spinosa Linn'
607. Journal:'Chemistry of Natural Compounds' Year:'2007' Volume:'43' Page:'239' DOI:'' Title:'CHEMICAL COMPOSITION OF Cynara scolymus LEAVES'
630. Journal:'Phytomedicine' Year:'2010' Volume:'17' Page:'940' DOI:'10.1016/j.phymed.2010.03.002' Title:'Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method'
658. Journal:'Journal of Ethnopharmacology' Year:'2007' Volume:'109' Page:'177' DOI:'10.1016/j.jep.2006.09.006' Title:'Punica granatum (pomegranate) and its potential for prevention and treatment of in?ammation and cancer'
820. Journal:'Not Bot Horti Agrobo' Year:'2013' Volume:'41' Page:'414' DOI:'' Title:'Chemical Composition of Celandine (Chelidonium majus L.) Extract and its Efects on Botrytis tulipae (Lib.) Lind Fungus and the Tulip'
841. Journal:'LWT - Food Science and Technology' Year:'2011' Volume:'44' Page:'875' DOI:'10.1016/j.lwt.2010.11.035' Title:'Chemical composition, mineral content and antioxidant activity of Verbena of?cinalis L'
858. Journal:'Indo Am. J. P. Sci' Year:'2019' Volume:'6' Page:'4138' DOI:'' Title:'CHEMICAL COMPOSITION OF ILLICIUM VERUM (STAR ANISE) FRUIT'
870. Journal:'International Journal of Food Studies' Year:'2020' Volume:'9' Page:'146' DOI:'10.7455/ijfs/9.1.2020.a2' Title:'Chemical Constituents in Leaves and Aroma Products of Nicotiana rustica L. Tobacco'
930. Journal:'Natural Product Communications' Year:'2011' Volume:'6' Page:'961' DOI:'' Title:'Phenolic Chemical Composition of Petroselinum crispum Extract and Its Effect on Haemostasis'
942. Journal:'Molecules' Year:'2018' Volume:'23' Page:'1247' DOI:'10.3390/molecules23061247' Title:'Exploring New Antioxidant and Mineral Compounds from Nymphaea alba Wild-Grown in Danube Delta Biosphere'
943. Journal:'BMC Complementary and Alternative Medicine' Year:'2017' Volume:'17' Page:'52' DOI:'10.1186/s12906-017-1561-2' Title:'Profile of bioactive compounds in Nymphaea alba L. leaves growing in Egypt: hepatoprotective, antioxidant and anti-inflammatory activity'
947. Journal:'Plants' Year:'2019' Volume:'8' Page:'40' DOI:'10.3390/plants8020040' Title:'Traditional Medicine Plant, Onopordum acanthium L. (Asteraceae): Chemical Composition and Pharmacological Research'
970. Journal:'Biocatalysis and Agricultural Biotechnology' Year:'2019' Volume:'19' Page:'101163' DOI:'10.1016/j.bcab.2019.101163' Title:'Datura innoxia and Dipsacus laciniatus: Biological activity and phenolic composition'